NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional)

Award Info:

Pioneer awardees are required to commit the major portion (more than 6 person-months or at least 51%) to activities supported by the Pioneer Award research project in the first three years of the project period.

Awards will be for $700,000 in direct costs per year, 5 years max


In the Pioneer Award program, emphases are on the qualities of the investigator, the innovativeness, and potential impact of the proposed research. Preliminary data and detailed experimental plans are not requested. To be considered pioneering, the proposed research must reflect substantially different ideas from those being pursued in the investigator’s current research program or elsewhere. The Pioneer Award is not intended to expand a current research program into the area of the proposed project. While the research direction may rely on the applicant’s prior work and expertise as its foundation, it cannot be an obvious extension or scale-up of a current research enterprise which may be competitive as a new or renewal R01 application. Rather, the proposed project must reflect a fundamental new insight, and which may involve exceptionally innovative approaches and/or radically unconventional hypotheses.